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GER: Animal Protection Research Prize 2014 of Hessen awarded

The Minister of the Environment for the State of Hessen, Priska Hinz, awarded the Animal Protection Research Prize 2014 of Hessen on November 18, 2014. The prize was split between two winners:

Prof. Dr Thorsten Stiewe of the Philips University in Marburg was awarded € 10,000 for his work on developing a method to monitor transplanted tumors in mice. The method allows moni­toring of two different tumor cell populations in vivo by marking them with luciferases and detecting light emission in blood sam­ples. The light emission is related to the total tumor size. This method reduces the number of animals needed for such studies, is less invasive than previous methods and can determine the size of the tumors more sensitively, allowing evaluations at ear­lier stages of tumor growth, thus refining the experiment.


Dr Stefan Weigt from Merck, Darmstadt received € 5,000 for his work on the development of an in vitro zebrafish embryo teratogenicity test. This test is based on a method previously developed by Dr Thomas Broschard and Francois Busquet to replace the use of rats and rabbits in determining the potential of substances to interfere with embryonal development. The im­proved method now reflects then entire embryonal development and no longer requires activation of the test substances by mam­malian tissue, thus allowing a further reduction in the use of experimental animals. The test detects the teratogenic potential of the anticoagulant warfarin, which is false-negative in other in vivo and in vitro tests for teratogenicity.


The prize has been awarded since 2005 to scientists or com­panies that are scientifically active in the state of Hessen.



Adapted from press release 364

Hessian Ministry for Environment, Climate Protection, Agriculture and Consumer Protection,

November 18, 2014

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