EU: JRC hepatotoxicity datasets available within ToxBank Data Warehouse
The ToxBank project, aimed at supporting the data management and analysis activities carried out across the Alternative Testing Strategies SEURAT-1 program, has launched a centralized compilation of data for systemic toxicity – the ToxBank Data Warehouse – for which public access is now available upon request Data generated under the SEURAT-1 research program and additional public data are being uploaded and integrated whenever possible into computerized models capable of predicting repeated-dose toxicity. The ToxBank Data Warehouse will use the ISA-TAB file format for interchange, storage and query of any investigation data, including dose-response and omics results.
In August, the European Commission Joint Research Centre made available via the ToxBank Data Warehouse the complete data sets derived from a JRC study on hepatotoxicity screening, in which a mode-of-action targeted analysis of the literature was used to identify toxicity pathways and the key biological events associated with them.
A detailed demonstration of the ToxBank Data Warehouse is available on-line at: http://www.toxbank.net/video/toxbank-demo-wc9
Users may access protocols or data that have been made available within the ToxBank Data Warehouse. The managers of the application also provide a request option to support the incorporation of relevant data generated outside of SEURAT-1 activities.
Public access may be requested at: http://www.toxbank.net/enquiries/request-data-warehouse-access
Tutorials on the use of the ToxBank resources are made available at: http://www.toxbank.net/library
Adapted from http://ihcp.jrc.ec.europa.eu/whats-new
August 30, 2014
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