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EU: EURL ECVAM issues recommendations on Keratosens

The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) has issued final recommendations on the use of the KeratinoSens™ assay for skin sensitization testing. EURL ECVAM recommended that KeratinoSens was useful in distinguishing sensitizers from nonsensitizers and could be used in an integrated approach with complementary information from other assays to determine skin sensitization potential. However, KeratinoSens should not be considered a stand-alone full replacement method. EURL ECVAM found the KeratinoSens assay to be transferable to laboratories experienced in cell culture and reproducible within and between laboratories.


More information:


Iccvam-all Digest, Vol 88, Issue 2

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