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Editorial Franz P. Gruber
FOOD FOR THOUGHT Thomas Hartung and Sebastian Hoffmann: Food for thought … on in silico methods in toxicology
MAIN ARTICLES Angelo Vedani, Martin Smiesko, Morena Spreafico, Ourania Peristera and Max Dobler: VirtualToxLab™ – In silico prediction of the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. Two years and 2,000 compounds of experience: a progress report
Ina Hagelschuer, Peter Hauff, Anne Strube, Sanna-Maria Käkönen and Georges von Degenfeld: Luminescent imaging technology as an opportunity to reduce and refine animal experiments: light at the end of the tunnel?
t4-REPORT Costanza Rovida and Thomas Hartung: Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the Transatlantic Think Tank for Toxicology (t4)
ECHA press release: New study inaccurate on the number of test animals for REACH
SHORT COMMUNICATIONS Olavi Pelkonen, Ari Tolonen, Timo Rousu, Larissa Tursas, Miia Turpeinen, Juho Hokkanen, Jouko Uusitalo, Michel Bouvier d’Yvoire and Sandra Coecke: Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis
Richard Vogel: Alternatives to the use of animals in safety testing as required by the EU-Cosmetics Directive 2009
POSITION STATEMENT Interspecies crosses: aspects of animal protection A position statement of the Ethics Committee for Animal Studies of the Swiss Academy of Medical Sciences (SAMS) and the Swiss Academy of Sciences (SCNAT) CONFERENCE REPORT Rome, Italy: 7th World Congress on Alternatives & Animal Use in the life Sciences Kenya: First Pan-African Seminar on Alternatives to Animal experiments
NEWS CAATfeed CH: Doerenkamp-Zbinden Award 2009 CH: ALTEX Awards for Marcel Leist et al. and Thomas Hartung CH: Roche joins forces to innovate toxicity testing and to reduce animal experimentation EU: EFSA's Scientific Committee promotes alternatives to animal testing EU: Two open calls for scientists at ECVAM EU: Open Call for Tender at ECVAM GER: Toxicologist wanted for commenting animal test proposals under REACH GER: 20 years ZEBET IND: A new Doerenkamp chair established in India NL: Dieter Lütticken Award 2008 OECD/USA: Animal-free testing of severe eye irritation USA: News from NICEATM and ICCVAM USA: IIVS News USA: Pfizer and US EPA enter into agreement to exchange data USA: Russell and Burch Award 2009 for Thomas Hartung USA: National Academy of Sciences wins 2009 CAAT Recognition Award USA: 2009 Charles River Laboratories’ Excellence in Refinement Award WC7: Balls, Goldberg and Spielmann named “Patrons of animal welfare in the life sciences” WC7: Doerenkamp-Zbinden Poster Awards
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