Chronicle of the ALTEX Award

In December 1997 the Foundation Board of the Fonds fuer versuchstierfreie Forschung (FFVFF), now AnimalfreeResearch, and at that time owner of ALTEX, decided to establish an annual award for the best article published in ALTEX. The award was endowed with 2.000 CHF including an invitation to the award ceremony at the next Linz congress and a 5 year MEGAT (now EUSAAT) membership.

The Society ALTEX Edition, founded in 2006, continued the tradition of the award, however without the MEGAT/EUSAAT membership. The Doerenkamp-Zbinden Foundation has generously sponsored the ALTEX Award since 2014.

The members of the ALTEX Board, Editorial Board and Editorial Office elect the winner of the annual award out of all main articles published in the previous year; articles including members of the ALTEX Board and Editorial Office as first or last authors are excluded. The award is presented to the first author, but all authors are mentioned on the certificate.


ALTEX Award Winners


Uwe Marx et al., TissUse GmbH, Berlin, Germany

Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.

ALTEX 33, 272-321.


Heike A. Behrensdorf-Nicol et al., Paul-Ehrlich Institute, Langen, Germany

“BINACLE” assay for in vitro detection of active tetanus neurotoxin in toxoids

ALTEX 32, 137-142.

doi: 10.14573/altex.1412181



Sarah E. Cavanaugh et al., Physicians Committee for Responsible Medicine, Washington, D.C., USA

Animal models of Alzheimer disease: historical pitfalls and a path forward

ALTEX 31, 279-302.

doi: 10.14573/altex.1310071



Miriam N. Jacobs et al., European Food Safety Authority, Parma, Italy

In vitro metabolism and bioavailability tests for endocrine active substances: What is needed next for regulatory purposes?

ALTEX 30, 331-351.

doi: 10.14573/altex.2013.3.331



Fransisca Leonard et al., Saarland University, Saarbruecken, Germany

Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model

ALTEX 29, 275-285.

doi: 10.14573/altex.2012.3.275


Erwin van Vliet, CAAT, Johns Hopkins University, Baltimore, USA

Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century

ALTEX 28, 17-44.

doi: 10.14573/altex.2011.1.017



Phillip B. Kuegler, Doerenkamp-Zbinden Chair for in vitro toxicology and Biomedicine, University of Konstanz, Germany

Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing

ALTEX 27, 17-42.



Costanza Rovida, Private Consultant, Varese, Italy

Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the Transatlantic Think Tank for Toxicology (t4)

ALTEX 26, 187-208.



Thomas Hartung, CAAT, Johns Hopkins University, Baltimore, USA

Food for thought …. on animal tests

ALTEX 25, 3-9.



Marcel Leist, Doerenkamp-Zbinden Chair for in vitro toxicology and Biomedicine, University of Konstanz, Germany

The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy

ALTEX 25, 163-190.



Marie-Jeanne W. A. Schiffelers et al., Utrecht University, Utrecht School of Governance (USG), The Netherlands

Factors stimulating or obstructing the implementation of the 3Rs in the regulatory process

ALTEX 24, 271-278.



Arianna Ferrari, Technical University of Darmstadt, Darmstadt, Germany

Genetically modified laboratory animals in the name of the 3Rs?

ALTEX 23, 294-307.



Marion Krug et al., Paul-Ehrlich Institute, Langen, Germany

Serologische Testmethoden als Ersatzfür Infektionsversuche an Ferkeln zur Wirksamkeitsprüfung von E.coli-Muttertierimpfstoffen

(Serological test methods as replacement for infection trials in piglets to test the potency of E. coli vaccines for sows (dams)) - article in German

ALTEX 22, 111-116.


Mahtab Bahramsoltani and Johanna Plendl, Free University, Berlin, Germany

Ein neues in vitro Modell zur Quantifizierung der Angiogenese

(A new in vitro model to quantify angiogenesis) - article in German

ALTEX 21, 227-244.



Oliver Reuthebuch et al., University Hospital, Zurich, Switzerland

Vollsynthetisches Trainingsmodell für die Koronarchirurgie: die Abkehr von Tierversuchen?

(Totally artificial training model for coronary heart surgery: the end of animal experiments?) - article in German

ALTEX 20, 17-20.



Nina Schweigert et al., EAWAG, Swiss Federal Institute for Environmental Science and Technology, Duebendorf, Switzerland

Ecotoxicological assessment of surface waters: a modular approach integrating in vitro methods

ALTEX 19, Suppl., 1, 30-37.



Heinrich W. Grosse, Pastoralsoziologisches Institut (PSI) der Evangelischen Fachhochschule Hannover, Germany

Christliche Verantwortung und Experimentelle Medizin. Versuche mit und am Menschen, Tierversuche
(Christian responsibility and experimental medicine; Experiments with and on humans; experiments on animals) - article in German

ALTEX 19, 195-202.



Christiane Gindorf et al., Across Barriers GmbH, Saarbruecken, Germany

Markertransport über biologische Barrieren in vitro: Vergleich von Zellkulturmodellen für die Dünndarmschleimhaut, die Blut-Hirn Schranke und das Alveolarepithel der Lunge

(Marker Transport across biological barriers in vitro: Comparison of cell culture models for the gastrointestinal barrier, the blood-brain barrier and the alveolar epithelium of the lung) article in German

ALTEX 18, 155-164.



Cornelia B. Reininger Vascular Center, University of Munich, Germany

The cell function analyser (CFA) – a physiological in vitro vascular model and potential alternative to animal experiments

ALTEX 17, 115-125.



Guntolf Herzberg, Berlin, Germany

Was kann „ethisches Abwägen“ im Tierversuch bedeuten?

(What is "ethical weighing" in animal testing?) - article in German

ALTEX 16, 255-266.



No award



Elvira Ebert et al., Paul-Ehrlich Institute, Langen, Germany

Serologische Wirksamkeitsprüfung von Clostridium perfringens-betatoxoidhaltigen Veterinärimpfstoffen - eine Alternative zum gesetzlich vorgeschriebenen Mäuseneutralisationstest
(An In Vitro Alternative to the Mouse Neutralisation Assay for Potency Testing of Betatoxoid containing Clostridium Perfringens Type Vaccines for Veterinary Use) - article in German

ALTEX 13, 68-75.


Optimierung und Etablierung von serologischen Methoden für die Wirksamkeitsprüfung von Immunglobulinen gegen Clostridium tetani-Toxoid
(Optimisation and establishing of serological methods for the potency testing of immunglobulins against Clostridium tetani-toxin) - article in German

ALTEX 15,Suppl., 30-32.


Entwicklung und Prävalidierung yon Alternativmethoden zur Wirksamkeitsprüfung von Clostridium perfringens-Impfstoffen

(Development and prevalidation of alternative methods for the potency testing of C. perfringens vaccines) - article in German

ALTEX 15, Suppl., 59-61.






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