ALTEX Archive - Supp. Linz 03/2004


Editorial

Contents

Main articles
IN VITRO TOXICOLOGY
Jing Yuan, Liegang Liu, Masashi Shimada, Aiguo Wang, Maren Ruhnke, Peter Heeckt, Andrea R. Muller, Natascha C. Nussler, Peter Neuhaus and Andreas Nüssler

Induction, expression and maintenance of cytochrome P450 isoforms in long-term cultures of primary human hepatocytes

Claudia Schleger, Stefan J. Platz and Ulrich Deschl

Development of an in vitro model for vascular injury with human endothelial cells

ECOTOXICOLOGY
Alexius Freyberger and Gabriele Scholz
Endocrine Toxicology - contributions of in vitro methods to the 3R concept

TOXICOPROTEOMICS
Michaela Kröger, Jürgen Hellmann, Luca Toldo, Matthias Glückmann, Bettina vonEiff, Kerstin Fella und Peter-Jürgen Kramer
Toxicoproteomics: first experiences in a BMBF-study

HUMAN STEM CELLS
Martina Klemm and André Schrattenholz
Neurotoxicity of active compounds - establishment of hESC-lines and proteomics technologies forhuman embryo- and neurotoxicity screening and biomarker identification

ISOLATED ORGANS
Michael Braun and Manfred Kietzmann
Ischemia reperfusion injury in the isolated hemoperfused bovine uterus - a model for the investigation of anti-inflammatory substances?


IN VITRO DRUG PERMEATION
Udo Bock, Thomas Flötotto and Eleonore Haltner
Validation of cell culture models for the intestine and the blood-brain barrier and comparison of drug permeation

BIOLOGICS
Ute Rosskopf-Streicher, Peter Volkers, Kerstin Noeske and Esther Werner
Quality assurance of C. perfringens epsilon toxoid vaccines -
ELISA versus mouse neutralisation test


BIOELECTRONICS AND BIOINFORMATICS
Angela M. Otto, Martin Brischwein, Elena Motrescu, Eléonore Cabala, Helmut Grothe, Christoph Stepper und Bernhard Wolf
Chips instead of mice: Cells on bioelectronic sensor-chips as an alternative to animal experiments

Stefan Plontke, Norbert Siedow, Hartmut Hahn, Raimund Wegener, Hans-Peter Zenner und Alec N. Salt
1D-and 3D- computer simulation for planning and interpretation of pharmacokinetic studies in the inner ear after round window drug delivery

PROGRAM

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