Spec. Issue 2006 - Article Summary

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ICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps

Karen Hamernik1, Chantra Eskes2, Jill Merrill 3, Neepa Choksi4, David Allen4, James Truax4,
Raymond Tice5, Marilyn Wind 6, Leonard M. Schechtman7 and William Stokes5

1US EPA*, 2ECVAM, 3US FDA, 4ILS, 5NICEATM/NIEHS, 6US CPSC, 7US FDA
Summary
A scientific symposium on the Mechanisms of Chemically Induced Ocular Injury and Recovery was held on May 11-12, 2005 in the USA. It was organised and co-sponsored by ICCVAM, NICEATM/NIEHS, and ECVAM, with support from COLIPA. A major goal was to identify research needed to advance the development of test systems that meet regulatory testing requirements and provide for human health protection while reducing, refining (less pain and distress), and/or replacing the use of animals. This paper (one of three), provides
a symposium overview and summarises the Session 3 discussions on mechanisms and biomarkers of chemically induced ocular injury and recovery.

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