Spec. Issue 2006 - Article Summary

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Good science must be the key factor in the development and use of alternative methods for safety assessment of cosmetics

Vera Rogiers and Marleen Pauwels
Dept. of Toxicology, Vrije Universiteit Brussel, Belgium
Summary
The most striking features of the current EU cosmetic legislation are its animal testing and marketing ban. As the legally imposed timeframe has mainly been introduced by political considerations, the key question remains whether replacement of all in vivo tests is scientifically feasible. The overview of the current status of 3R alternatives and related deadlines provided by ECVAM were commented by the SCCNFP. In this paper, repeated dose toxicity testing is discussed to show that innovation is taking place but cannot be governed by political pressure. The opening up of the field of alternatives and the creation of a positive atmosphere towards good science are highly needed.

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