Spec. Issue 2006 - Article Summary

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A wider interpretation of the three Rs model

Flavia Zucco
Istituto di Neurobiologia e Medicina Molecolare, CNR, Roma, Italia
The project Anim.Al.See, which aims to update the 3Rs model, has explored in detail, both from the philosophical and the scientific point of view, the issue of alternatives to animal experimentation. Concepts and language involved in specific case studies related to each R have been analysed. On this basis, new definitions, among others of replacement, reduction, and refinement, have been coined in order to implement a more advanced version of the Russell and Burch model. This has been achieved by widening the framework of reference and thus offering a wider range of approaches.

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