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Production of Monoclonal Antibodies in Chicken Eggs

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Andreas Hlinak¹, Uwe Marx² and Volker Jäger³
¹Institut für Virologie, FB Veterinärmedizin (Standort Mitte) der Freien Universität Berlin;
²Institut für Medizinische Immunologie, Universitätsklinikum (Charité) der Humboldt-Universität Berlin; ³Gesellschaft für Biotechnologische Forschung mbH, Braunschweig

Summary

The possibility to produce monoclonal antibodies in chicken eggs was shown. Knowledge of biochemical and biophysical parameters of eggs were the basic of the experiments. The cell clones produced 0.1 mg/ml of antibodies in the egg fluid. This method can be an alternative to the monoclonal antibody production in mouse ascites or in bioreactors.



ALTEX 11(2), 85-91

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