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Proposal for a Brazilian centre on alternative test methods

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Chantra Eskes1, Vanessa de Moura Sá-Rocha2, Jadir Nunes3, Octavio Presgrave4, Dermeval de Carvalho5, Philippe Masson6, Ekaterina Rivera7, Sandra Coecke8, Joachim Kreysa8 and Thomas Hartung9
1 Independent Consultant, Ispra, Italy;
2 Natura, Cajamar, SP, Brazil;
3 Brazilian Association of Cosmetology, São Paulo, SP, Brazil;
4 National Institute of Quality Control in Health (INCQS), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, RJ, Brazil;
5 Biotox, Ribeirão Preto, SP, Brazil;
6 EVIC International, Paris, France;
7 Biological Science Institute, Federal University of Goiás, Brazil;
8 ECVAM, In Vitro Methods Unit, Institute for Health and Consumers Protection, European Commission Joint Research Center, Ispra, Italy;
9 Johns Hopkins University, Baltimore, USA and University of Konstanz, Germany


Several initiatives have recently taken place in Brazil in order to foster the creation of centers dedicated to alternatives to animal testing. In 2008, Vanessa Sá-Rocha organized a meeting with Brazilian regulatory authorities and the major stakeholders in the field of testing to foster discussions on the process of funding, development, and validation of alternative methods in Brazil. Octavio Presgrave published a scientific article on “The Need for the Establishment of a Brazilian Centre for the Validation of Alternative Methods.” Also in 2008, Jadir Nunes, together with Dermeval de Carvalho, prepared and presented a proposal to the Brazilian National Agency of Health Surveillance (ANVISA) for the creation of a Centre for the Validation of Alternative Methods. ECVAM and other European stakeholders have been involved in the initiatives. Furthermore, also in 2008, a new legislation has been adopted in Brazil regarding the use of animals for scientific purposes (“lei Arouca”). The legislation establishes, among other provisions, the task of monitoring and evaluating the introduction of alternative methods. However, the legislation does not provide for promotion of or information about, existing alternative methods to the larger Brazilian scientific community. In order to streamline the different activities, Chantra Eskes acted as a facilitator by establishing a new joint proposal with the current Brazilian stakeholders, aimed at setting up a Brazilian Center on Alternative Test Methods.

ALTEX 26(4), 303-306
doi: 10.14573/altex.2009.4.303

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