ALTEX Archiv - Suppl. 2007 To archive overview EDITORIAL Peter Maier: Presenting a special issue of ALTEXHugo Wick: The 3R Research Foundation Switzerland CONTENTS COMPLETED PROJECTS Pierre Aeby, François Python and Carsten Goebel: Skin sensitisation: Understanding the in vivo situation for the development of reliable in vitro test approaches Margarete Arras: Improvement of pain therapy in laboratory mice Yara Banz and Robert Rieben: Exploring natural anticoagulation by endothelial cells: A novel in vitro model Nicolau Beckmann: Non-invasive methods: Investigation of airways diseases by MRI in rats Gerd Bicker, Andrea Gierse, Saime Tan and François Paquet-Durand: Simulation of stroke-related damage in cultured human nerve cells Frank O. Bootz and Felix R. Wolf: Animal-free screening of biological materials for contamination by rodent viruses Arie Bruinink and Peter Maier: Identification of neurotoxic chemicals in cell cultures Karl Fent: Permanent fish cell cultures as important tools in ecotoxicology Andrew Hemphill: Generation of parasite cysts in cultured cells instead of living animals Paul Honegger and Beatriz Pardo: Aggregating brain cell cultures: Investigation of stroke related brain damage Rok Humar, Lourdes Sanchez de Miguel, Fabrice N. Kiefer, Edouard J. Battegay: Formation of new blood vessels in the heart can be studied in cell cultures Thomas Kröber and Patrick Guerin: The tick blood meal: From a living animal or from a silicone membrane? Regine Landmann-Suter: Generation and use of a mouse Kupffer cell line Claudia Mertens and Thomas Rülicke: Welfare assessment and phenotype characterisation of transgenic mice Werner J. Pichler: Predicting drug hypersensitivity by in vitro tests Valeska Reichel, Carsten Baehr and Gert Fricker: From blood to brain and vice versa: Transport processes in choroid plexus can be studied in vitro R. Geoff Richards, Martin J. Stoddart, Angharad E. Simpson and Pamela I. Furlong: Establishing a 3D ex vivo culture system for investigations of bone metabolism and biomaterial interactions Stephanie Schindler, Stefan Fennrich, Reto Crameri, Thomas W. Jungi, Thomas Montag, Thomas Hartung: Fever in the test tube – towards a human(e) pyrogen test Angelo Vedani, Markus A. Lill and Max Dobler: Predicting the toxic potential of drugs and chemicals in silico Eva Waiblinger and Barbara König: Housing and husbandry conditions affect stereotypic behaviour in laboratory gerbils 67 Hanno Würbel: Environmental enrichment does not disrupt standardization of animal experiments PROJECTS IN PROGRESS Anna Bogdanova and Johannes Vogel: Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation Paolo Cinelli: Assessment of pain and stress in mice by monitoring gene expression changes Pierre Cosson: A non-mammalian system to study bacterial infections Beate Escher: Development of QSAR-models for classification and prediction of baseline toxicity and of uncoupling of energy transduction Beate Escher and Jung-Hwan Kwon: Development of an in vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish system Paul Flecknell, Jon Gledhill and Claire Richardson: Assessing animal health and welfare and recognising pain and distress Marianne Geiser and Doris Lang: In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction Norbert Goebels: Organotypic CNS slice cultures as an in vitro model for immune mediated tissue damage and repair in multiple sclerosis Regina Hofmann-Lehmann and Ludwig Hoelzle: Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas Cynthia Lee and Mauro Alini: The development of an in vitro intervertebral disc organ culture Stephen L. Leib: An in vitro model of central nervous system infection and regeneration: Neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis Alexander Mathis: Development of a three-dimensional enteric cell culture model for In vitro studies of the intestinal eukaryotic parasites Cryptosporidium spp. Christoph Mueller: Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets Omolara Ogunshola: Development of a novel multicellular 3-dimensional blood brain barrier in vitro model Elisabetta Padovan: Adjuvanticity of microbial-derived particles and synthetic analogs in vitro Nicolas Ruggli and Artur Summerfield: Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates Claudio Strebel: Information on serum free cell lines, an interactive database AUTHORS INDEXSUBJECT INDEXGUIDELINES FOR AUTHORSImprint