ALTEX Archive - 4/11


Editorial
Sonja von Aulock

Contents

FOOD FOR THOUGHT

Paul A. Locke and D. Bruce Myers, Jr
A replacement-first approach to toxicity testing is necessary to successfully reauthorize TSCA 

MAIN ARTICLES
t4 report:
Costanza Rovida, Fabiola Longo, and Richard R. Rabbit
How are reproductive toxicity and developmental toxicity addressed in REACH dossiers? 

María Moreno-Villanueva, Tobias Eltze, Dirk Dressler, Jürgen Bernhardt, Cordula Hirsch, Peter Wick, Gudrun von Scheven, Kirsten Lex, and Alexander Bürkle
The automated FADU-assay, a potential high-throughput in vitro method for early screening of clastogenicity 

Caroline Rauch, Elisabeth Feifel, Eva-Maria Amann, Hans Peter Spötl, Harald Schennach, Walter Pfaller, and Gerhard Gstraunthaler
Alternatives to the use of fetal bovine serum: Human platelet lysates as a serum substitute in cell culture media 

Jenny Stracke, Bettina Bert, Heidrun Fink, and Jörg Böhner
Assessment of stress in laboratory Beagle dogs constrained by a Pavlov sling 

t4 report:
Nina Hasiwa, Jarrod Bailey, Peter Clausing, Mardas Daneshian, Marianne Eileraas, Sándor Farkas, István Gyertyán, Robert Hubrecht, Werner Kobel, Goran Krummenacher, Marcel Leist, Hannes Lohi, Ádám Miklósi, Frauke Ohl, Klaus Olejniczak, Georg Schmitt, Patrick Sinnett-Smith, David Smith, Kristina Wagner, James D. Yager, Joanne Zurlo, and Thomas Hartung
Critical evaluation of the use of dogs in biomedical research and testing in Europe 

t4 report:
Mardas Daneshian, Mohammad A. Akbarsha, Bas Blaauboer, Francesca Caloni, Pierre Cosson, Rodger Curren, Alan Goldberg, Franz Gruber, Frauke Ohl, Walter Pfaller, Jan van der Valk, Pilar Vinardell, Joanne Zurlo, Thomas Hartung, and Marcel Leist
A framework program for the teaching of alternative methods (replacement, reduction, refinement) to animal experimentation 

COMMENT
Franz P. Gruber
The Basel Declaration: a critical appraisal 

WORKSHOP REPORT

Joanne Zurlo et al.
Critical evaluation of the use of dogs in biomedical research and testing 

CONGRESS REPORT

Franz P. Gruber and Sonja von Aulock
8th World Congress on Alternatives and Animal Use in the Life Sciences: The Three Rs – Together it’s possible 

CORNERS
CAATfeed
Ecopa
ICCVAM/NICEATM 

NEWS
BRA: Brazilian Center for Validation of Alternative Methods established
EU: Review of REACH in 2012
GER: Berlin research prize for alternatives to animal experiments awarded
GER: Ethics prize for Paola Cavalieri and Peter Singer
INT: Official approval of OECD TG 443 - Extended 1-Generation Reproductive Toxicity Study
INT: “Basel meets Berlin” – transparency is needed for animal experiments
NL: International course in laboratory animal science
UK: Dr Hadwen Trust announces funding opportunity
UK: InterNICHE honored for replacement of animal experiments in RSPCA award
UK: ECEAE seeks toxicologist
UK: NC3Rs kick off CRACK-IT challenges competition
USA: CAAT to pioneer transformative research in toxicology testing 

CALENDAR OF EVENTS
INSTRUCTIONS FOR AUTHORS
IMPRINT


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