Editorial Sonja von Aulock
FOOD FOR THOUGHT Paul A. Locke and D. Bruce Myers, Jr: A replacement-first approach to toxicity testing is necessary to successfully reauthorize TSCA
MAIN ARTICLES t4 report: Costanza Rovida, Fabiola Longo, and Richard R. Rabbit: How are reproductive toxicity and developmental toxicity addressed in REACH dossiers?
María Moreno-Villanueva, Tobias Eltze, Dirk Dressler, Jürgen Bernhardt, Cordula Hirsch, Peter Wick, Gudrun von Scheven, Kirsten Lex, and Alexander Bürkle: The automated FADU-assay, a potential high-throughput in vitro method for early screening of clastogenicity
Caroline Rauch, Elisabeth Feifel, Eva-Maria Amann, Hans Peter Spötl, Harald Schennach, Walter Pfaller, and Gerhard Gstraunthaler: Alternatives to the use of fetal bovine serum: Human platelet lysates as a serum substitute in cell culture media
Jenny Stracke, Bettina Bert, Heidrun Fink, and Jörg Böhner: Assessment of stress in laboratory Beagle dogs constrained by a Pavlov sling
t4 report: Nina Hasiwa, Jarrod Bailey, Peter Clausing, Mardas Daneshian, Marianne Eileraas, Sándor Farkas, István Gyertyán, Robert Hubrecht, Werner Kobel, Goran Krummenacher, Marcel Leist, Hannes Lohi, Ádám Miklósi, Frauke Ohl, Klaus Olejniczak, Georg Schmitt, Patrick Sinnett-Smith, David Smith, Kristina Wagner, James D. Yager, Joanne Zurlo, and Thomas Hartung: Critical evaluation of the use of dogs in biomedical research and testing in Europe
t4 report: Mardas Daneshian, Mohammad A. Akbarsha, Bas Blaauboer, Francesca Caloni, Pierre Cosson, Rodger Curren, Alan Goldberg, Franz Gruber, Frauke Ohl, Walter Pfaller, Jan van der Valk, Pilar Vinardell, Joanne Zurlo, Thomas Hartung, and Marcel Leist: A framework program for the teaching of alternative methods (replacement, reduction, refinement) to animal experimentation
COMMENT Franz P. Gruber: The Basel Declaration: a critical appraisal
WORKSHOP REPORT Joanne Zurlo et al.: Critical evaluation of the use of dogs in biomedical research and testing
CONGRESS REPORT Franz P. Gruber and Sonja von Aulock: 8th World Congress on Alternatives and Animal Use in the Life Sciences: The Three Rs – Together it’s possible
CORNERS CAATfeed Ecopa ICCVAM/NICEATM
NEWS BRA: Brazilian Center for Validation of Alternative Methods established EU: Review of REACH in 2012 GER: Berlin research prize for alternatives to animal experiments awarded GER: Ethics prize for Paola Cavalieri and Peter Singer INT: Official approval of OECD TG 443 - Extended 1-Generation Reproductive Toxicity Study INT: “Basel meets Berlin” – transparency is needed for animal experiments NL: International course in laboratory animal science UK: Dr Hadwen Trust announces funding opportunity UK: InterNICHE honored for replacement of animal experiments in RSPCA award UK: ECEAE seeks toxicologist UK: NC3Rs kick off CRACK-IT challenges competition USA: CAAT to pioneer transformative research in toxicology testing
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