Editorial Franz P. Gruber
WORKSHOP REPORT 21st Century Validation Strategies for 21st Century Tools:
Joanna Jaworska and Sebastian Hoffmann: Integrated Testing Strategy (ITS) – opportunities to better use existing data and guide future testing in toxicology
Kim Boekelheide and Melvin E. Andersen: A mechanistic redefinition of adverse effects – a key step in the toxicity testing paradigm shift
Thomas Hartung: Evidence-based toxicology – the toolbox of validation for the 21st century?
Daniel R. Dietrich: Courage for simplification and imperfection in the 21st century assessment of “endocrine disruption”
Deborah Rudacille: Summary of the July 2010 Workshop, “21st Century Validation Strategies for 21st Century Tools”
MAIN ARTICLE Thomas Hartung: Comparative analysis of the revised Directive 2010/63/EU for the protection of laboratory animals with its predecessor 86/609/EE C – a t4 report
SHORT COMMUNICATION Laura Ducceschi, Nicole Green and Crystal Miller-Spiegel: Dying to learn: the supply and use of companion animals in U.S. colleges and universities
FOOD FOR THOUGHT Marcel Leist, Liudmila Efremova and Christiaan Karreman: Food for thought ... considerations and guidelines for basic test method descriptions in toxicology
CONFERENCE REPORT Linz 2010: Session Nanotoxicology
NEWS EU: EU plans to delay ban of animal experiments for cosmetics EU: Research animal use holds steady UK/USA: ATLA gets ARDF award USA: News from NICEATM and ICCVAM USA: NIH statement regarding stay of stem cell injunction USA: CAATfeed
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