Current Issue - 3/16



Sonja von Aulock





Thomas Hartung

E-cigarettes and the need and opportunities for alternatives to animal testing



Research article

Marco Cocorocchio, Robert Ives, David Clapham, Paul L. R. Andrews and Robin S. B. Williams

Bitter tastant responses in the amoeba Dictyostelium correlate with rat and human taste assays

Research article

Fawzy A. Elnady

The Elnady Technique: An innovative, new method for tissue preservation

Research article

Constança Carvalho, Mariana Vieira Crespo, Luísa Ferreira Bastos, Andrew Knight and Luís Vicente

Contribution of animal models to contemporary understanding of attention deficit hyperactivity disorder

Research article

Anna Kuehn, Stephanie Kletting, Cristiane de Souza Carvalho-Wodarz, Urska Repnik, Gareth Griffiths, Ulrike Fischer, Eckart Meese, Hanno Huwer, Dagmar Wirth, Tobias May, Nicole Schneider-Daum and Claus-Michael Lehr

Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier

Research article

Anke M. Tukker, Martje W. G. D. M. de Groot, Fiona M. J. Wijnolts, Emma E. J. Kasteel, Laura Hondebrink and Remco H. S. Westerink

Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?


t4 Workshop report

Uwe Marx, Tommy B. Andersson, Anthony Bahinski, Mario Beilmann, Sonja Beken, Flemming R. Cassee, Murat Cirit, Mardas Daneshian, Susan Fitzpatrick, Olivier Frey, Claudia Gaertner, Christoph Giese, Linda Griffith, Thomas Hartung, Minne B. Heringa, Julia Hoeng, Wim H. de Jong, Hajime Kojima, Jochen Kuehnl, Marcel Leist, Andreas Luch, Ilka Maschmeyer, Dmitry Sakharov, Adrienne J. A. M. Sips, Thomas Steger-Hartmann, Danilo A. Tagle, Alexander Tonevitsky, Tewes Tralau, Sergej Tsyb, Anja van de Stolpe, Rob Vandebriel, Paul Vulto, Jufeng Wang, Joachim Wiest, Marleen Rodenburg and Adrian Roth

Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing



Cristina Barbosa da Silva, Gabriel Mendes de Souza Martins and Walter Lilenbaum

Blood collection by gingival puncture on hamsters reduces animal number in leptospirosis virulence tests



Alexandra Maertens, Bruno Hubesch and Costanza Rovida

Two Good Read-across Practice workshops. Making it work for you!


CORNERS (download all Corners as pdf)








NEWS (download all News as pdf)

AUS: Planned ban on cosmetic products tested on animals

EU: REACH annexes amended – registrants to use alternative test methods

EU: ECHA requires considerations for alternative methods to be included in testing proposals

EU: Guide on avoiding new animal tests for REACH registration available

EU: Study on fish embryo toxicity test published

EU: Presentations of ECHA Workshop available

EU: EPAA 3Rs Science Prize open for submissions

GER: Call for tenders for the Felix Wankel Animal-Welfare-Research-Award 2017

GER: Science instead of Animal Experiments Congress

GER: Hamburg offers 3Rs research prize

INT: HIS/HSUS to fund publication of roadmaps to extend Tox21 to biosciences

INT: Deadline for AOP Awards extended

SUI: News from ALTEX

UK: From dogs to 3D tissue models: the 2015 3Rs Prize

UK: LUSH Prize nominations open

UK: Improving compliance with the ARRIVE guidelines

USA: 2017 Science-based Refinement Awards

USA: TSCA reform bill signed into law 


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